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This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with ? and ? thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.
This book reviews the pathophysiology and physical manifestations of acromegaly and discusses the multiple treatment options now available for the management of the patient with acromegaly. The book contains an ample number of illustrations that help to emphasize points of particular interest, including radiological, histopathological, and physical diagnosis images. Sections are devoted to detailing important topics including determinants of pathological effects of disease activity in acromegaly, individual therapeutic choices and criteria for diagnosis, and disease control.
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Bone and Soft Tissue Pathology: A Volume in the Diagnostic Pathology Series, by Andrew L. Folpe, MD and Carrie Y. Inwards, MD, packs today’s most essential bone and soft tissue pathology know-how into a compact, high-yield format! The book’s pragmatic, well-organized approach-complemented by abundant full-color, high-quality illustrations and at-a-glance tables-makes it easy to access the information you need to quickly and accurately identify pathology specimens. Best of all, Expert Consult functionality provides online access to the full text of the book, downloadable illustrations for your personal use, and more. The result is a practical, affordable reference for study and review as well as for everyday clinical practice.
*Includes access to the complete contents online, fully searchable, downloadable illustrations for your personal use, and more, allowing you to consult the text a quick, convenient manner.
*Reviews normal histology before examining abnormal findings, enabling you to conveniently compare their characteristics in one place at one time.
*Covers both neoplastic and non-neoplastic conditions of bone and soft tissue to equip you to meet a wide range of diagnostic challenges.
*Uses a consistent, user-friendly format to explore each entity’s clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations…making it easy to locate specific information on a particular entity.
*Features abundant boxes and tables throughout that enhance the presentation and accessibility of the material.
*Offers nearly 1,000 full-color, high-quality illustrations that demonstrate the key features of a wide variety of pathologic lesions to facilitate greater accuracy in identification of specimens.
The Foundations in Diagnostic Pathology Series answers the call for fresh, affordable, and easy-to-use guidance. Each region-specific volume provides all of the most essential information on the pathologic entities encountered in practice.
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