Breast Cancer Epidemiology

Contents

1 Global Burden of Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

Jacques Ferlay, Clarisse He´ ry, Philippe Autier,and Rengaswamy Sankaranarayanan

2 Breast Cancer Biology and Clinical Characteristics . . . . . . . . . . . . . . 21

Amanda I. Phipps and Christopher I. Li

3 In situ Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47

Brian L. Sprague and Amy Trentham-Dietz

4 Endogenous Hormones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73

Amanda I. Phipps and Christopher I. Li

5 Exogenous Hormones. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89

Christopher I. Li and Elisabeth F. Beaber

6 Reproductive Factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119

Mats Lambe

7 Physical Activity and Anthropometric Factors . . . . . . . . . . . . . . . . . . 137

Katherine D. Henderson, Jennifer Prescott,and Leslie Bernstein

8 Diet and Nutrition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153

Martin Lajous and Shumin M. Zhang

9 Environmental and Occupational Exposures . . . . . . . . . . . . . . . . . . . 183

Amanda I. Phipps, Dana Mirick, Christopher I. Li,and Scott Davis

10 Shift Work and Circadian Disruption. . . . . . . . . . . . . . . . . . . . . . . . . 223

Scott Davis and Dana K. Mirick

11 Non-Hormonal Medications and Chronic Diseases . . . . . . . . . . . . . . 243

Patricia F. Coogan

12 Male Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261

Ian S. Fentiman

13 Inherited Predisposition: Familial Aggregation and HighRisk Genes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277

Kathleen E. Malone and Kerryn W. Reding

14 Common Genetic Susceptibility Loci . . . . . . . . . . . . . . . . . . . . . . . . . 301

Mikkel Z. Oestergaard and Paul Pharoah

15 Mammographic Density as a Potential Surrogate Markerfor Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321

Norman F. Boyd, Lisa J. Martin, and Salomon Minkin

16 Breast Cancer Screening . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343

Karla Kerlikowske

17 Principles of Breast Cancer Therapy . . . . . . . . . . . . . . . . . . . . . . . . . 371

Allison W. Kurian and Robert W. Carlson

18 Breast Cancer Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389

Graham A. Colditz and Courtney Beers

Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 403

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